Product Overview
The Fully Automatic Organic Analyte Pre-concentrator & Purification System is an automated sample preparation platform designed for the purification and pre-concentration of trace organic analytes in water and other liquid samples.
The system integrates multiple sample preparation processes, including pre-filtration, solid phase extraction (SPE), analyte enrichment, impurity removal, purification, elution, reconstitution, and high-ratio pre-concentration.
It can be configured for a wide range of organic analytes, including but not limited to PFAS, pharmaceutical and drug residues, organic amines, organic acids, and other trace organic compounds.
Depending on the target compounds, sample matrix, and analytical method, a pre-concentration ratio of up to 1000× can be achieved, helping improve sensitivity for subsequent instrumental analysis while significantly reducing manual sample preparation.
Prepared samples can be used with analytical platforms such as HPLC, LC/MS, LC-MS/MS, GC/MS, and IC.
Key Functions
High-Ratio Pre-concentration
The system enriches and concentrates trace organic analytes prior to instrumental analysis. Depending on the application and method configuration, a pre-concentration ratio of up to 1000× can be achieved.
Automated Sample Preparation
Multiple sample preparation procedures can be performed automatically, including:
Pre-filtration
Solid phase extraction (SPE)
Target analyte enrichment
Sample purification
Removal of impurities and interfering compounds
Analyte elution
Sample reconstitution
Final volume adjustment and pre-concentration
Automation helps minimize manual handling while improving consistency and reproducibility of the sample preparation process.
Selective Enrichment of Target Compounds
Users can specify the target compounds or classes of compounds to be retained, enriched, and pre-concentrated.
Typical analytes may include:
PFAS
Pharmaceuticals and drug residues
Organic amines
Organic acids
Other trace organic contaminants
The system can be configured according to the chemical properties of the target analytes and the requirements of the downstream analytical method.
Selective Removal of Interferences
In addition to concentrating target analytes, the system can be configured to wash off, remove, or reduce selected interfering compounds and impurities.
This purification process provides a cleaner final sample and can improve the reliability of subsequent instrumental analysis.
Flexible Analyte Reconstitution
After enrichment and purification, target analytes can be reconstituted to a specified final volume using a selected solvent or solution, including:
Designated organic solvents
Organic solvent mixtures
Distilled water
Deionized water
Buffer solutions
Other specified solvent systems
The reconstitution conditions can be selected according to the requirements of downstream HPLC, LC/MS, LC-MS/MS, GC/MS, IC, or other analytical methods.
Compatible Analytical Platforms
Prepared samples can be used for subsequent analysis with a variety of analytical instruments, including:
HPLC — High-Performance Liquid Chromatography
LC/MS — Liquid Chromatography-Mass Spectrometry
LC-MS/MS — Liquid Chromatography-Tandem Mass Spectrometry
GC/MS — Gas Chromatography-Mass Spectrometry
IC — Ion Chromatography
Other compatible chromatographic and mass spectrometric platforms
Typical Applications
The system is suitable for applications requiring purification, enrichment, and high-ratio pre-concentration of trace organic compounds, including:
PFAS sample preparation
Trace organic contaminant analysis in environmental water
Drinking water and source water analysis
Pharmaceutical and drug residue analysis
Organic amine analysis
Organic acid analysis
Organic contaminant analysis in wastewater and industrial effluent
Complex sample preparation for research laboratories
Automated sample preparation prior to LC/MS, LC-MS/MS, GC/MS, and related analyses
Typical Workflow
Sample Introduction → Pre-filtration → Solid Phase Extraction → Target Analyte Enrichment → Matrix / Impurity Removal → Analyte Elution → Reconstitution with Designated Solvent → Pre-concentration / Final Volume Adjustment → Instrumental Analysis
Application-Specific Configuration
Different target compounds, sample matrices, and analytical methods may require different sample preparation conditions. The system can therefore be configured according to specific application requirements.
Before placing an order, users may provide information such as:
Target analytes or compound classes
Sample type and sample matrix
Major interfering compounds to be removed
Required pre-concentration ratio
Required final sample volume
Preferred reconstitution solvent
Downstream analytical instrument and method
Our technical team can discuss the application requirements with the user and develop an appropriate sample purification and pre-concentration configuration.
For specific target compounds or sample preparation requirements, please contact us for technical discussion before placing an order.